Switching to Vegan, Keto Diets Linked to Immune System, Gut Changes, Study Says, ET HealthWorld

New Delhi: Switching to a vegan diet may trigger responses associated with innate immunity, or the immune system one is born with, according to new research. On the other hand, research also found that switching to a keto diet – high in fat and low in carbohydrates – could trigger responses generally linked to adaptive immunity, which is the immune system that one develops with the time in response to external infections and vaccinations. .

Along with changes in the immune system, researchers at the National Institutes of Health in the United States also detected changes and alterations in the participants’ gut microbiome.

However, more research was needed before these immune and gut changes could be considered “beneficial” or “harmful”, they said in their study published in the journal Nature Medicine.

It is also not yet clear what impact these findings might have on therapeutic nutritional interventions – which involve changing diet to improve health – particularly in the context of diseases such as cancer or inflammatory diseases, said the ‘team.

For the study, researchers closely monitored various biological responses of 20 participants for two weeks. They were divided into two groups, each randomly assigned to a vegan or keto diet.

The team measured the effects of the diets using a “multiomics” approach, analyzing multiple datasets to assess the body’s biochemical, cellular, metabolic and immune responses, as well as changes in the microbiome.

After analyzing the data, they found that the keto diet affected more proteins in the blood and blood plasma, brain and bone marrow than the vegan diet.

They also found that the vegan diet promoted more red blood cell-related pathways, including those involved in hemoglobin production, likely due to the diet’s iron-rich content, they said.

The team also observed that people following a vegan diet, which contained 10 percent fat and 75 percent carbohydrates, chose to consume fewer calories than those following a keto diet, which included about 75 percent carbohydrates. fat and 10 percent carbohydrates.

The researchers said they detected distinct changes in metabolism and immune system resulting from the two diets, despite participants’ diversity in ethnicity, race, gender, body mass index (BMI) and weight. age.

The results showed that the immune system responded surprisingly quickly to nutritional interventions, they said, suggesting that it might be possible to tailor patients’ diets to prevent disease or complement treatments for the disease, such as for example by slowing down processes associated with cancer or neurodegenerative disorders.

Therefore, they said, additional studies are needed to examine the impact of these nutritional interventions on specific aspects of the immune system.

  • Published on January 31, 2024 at 2:21 p.m. IST

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